Optimization of simulated moving bed chromatography with fractionation and feedback incorporating an enrichment step
نویسندگان
چکیده
An enrichment step is proposed to simulated moving bed chromatography with fractionation and feedback (FF-SMB), a new variation of SMB, to concentrate recyclates before they are fed back into the unit. Effectiveness of this operation is evaluated by systematic optimization studies. Case studies reveal that enriching recyclates is advantageous to FF-SMB and provides further improvement in separation performance over the non-enriched case.
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تاریخ انتشار 2010